Back to portfolio

Flashback Technologies

Developing a new device and vital sign for early and actionable detection of imminent cardiovascular collapse

Flashback Technologies was founded by Drs. Steve Moulton and Greg Grudic in 2009 based on research conducted at the University of Colorado. The company developed and is refining the Compensatory Reserve Index to provide an “early warning” system to alert caregivers to a patient’s point of collapse. CRI is a new vital sign that monitors a patient’s central volume status from normovolemia to decompensation. CRI is calculated from the pulsatile component of the cardiac cycle, and can be derived from a variety of physiological waveforms and sensors. The company's FDA-cleared device utilizes the PPG or pulse oximetry waveform to provide caregivers continuous and real-time status of how far or near an individual patient may be from the point of decompensation. Research has demonstrated the technology to be 97% accurate in estimating individual-specific tolerance to central volume loss.